There aren't any other documented drug interactions between possibly naproxen or Skelaxin with Synthroid, phentermine, bupropion and escitalopram. Using both of those bupropion and naproxen together could cause an increased danger for gastrointestinal bleedingI happen to be on Wellbutrin XL (buproprion) for 6 months. I begun with 150 mg and just c